๐Ÿฉบ Health & Care

Disease Testing for Goats: CAE, CL, Johne's & More

Essential disease testing guide for goat herds. What CAE, CL, Johne's, and Q-Fever are, how to test, interpreting results, and building a disease-free herd.

Disease Testing for Goats: CAE, CL, Johne's & More

Last updated: July 2026 ยท 5 min read
The three infectious diseases every goat herd should test for are CAE, CL, and Johne's โ€” all chronic, often symptomless for years, and impossible to detect by inspection. Blood-test your whole herd annually and test every new animal (quarantining 30 days and retesting CAE at 60 days), because untested purchases are the most common way these diseases enter a clean herd.

Disease testing is the foundation of a healthy, marketable goat herd. The major infectious diseases โ€” CAE, CL, and Johne's โ€” can silently spread through a herd for years before symptoms appear. By then, most of the herd may be infected. Regular testing identifies infected animals, protects your clean animals, and gives buyers confidence in your herd's health status. If you sell goats, testing is not optional โ€” it is expected.

The Big Three

CAE (Caprine Arthritis Encephalitis)

CAE is a viral disease caused by a lentivirus (similar to HIV in structure, but not transmissible to humans). It causes chronic, progressive arthritis in adult goats and encephalitis (brain inflammation) in kids. There is no cure and no vaccine.

AspectDetails
TransmissionPrimarily through infected milk and colostrum (dam to kid). Also through direct contact with bodily fluids over prolonged close contact. Blood-to-blood transmission (shared needles, dehorning equipment).
SymptomsSwollen knees (big knee), chronic lameness, gradual wasting, hard udder (chronic mastitis form), poor milk production. Many infected goats show no symptoms for years.
TestBlood test (ELISA). Detects antibodies to the virus. Blood drawn by vet or owner (if state allows) and sent to an approved lab.
Cost$3 to $8 per animal per test
FrequencyTest annually. Test all new animals before introduction to your herd.
False negativesPossible in recently infected animals (antibodies take 2 to 8 weeks to develop) and in kids under 6 months (may have maternal antibodies). Retest suspicious animals 60 days later.
CAE prevalence: Estimated at 30 to 80% of US dairy goat herds have at least one positive animal. Many goats are asymptomatic carriers. Do not assume your herd is negative without testing. The most common source of CAE introduction is purchasing untested animals.

CL (Caseous Lymphadenitis)

CL is a chronic bacterial infection caused by Corynebacterium pseudotuberculosis that causes abscesses in lymph nodes. External abscesses are visible as lumps under the skin, typically around the head, neck, and shoulders. Internal abscesses affect the lungs, liver, and other organs and are not visible externally.

AspectDetails
TransmissionWhen an abscess ruptures, the pus is extremely contagious and contaminates the environment (soil, fences, feeders). Other goats are infected through skin wounds, abrasions, or mucous membranes. The bacteria can survive in soil for months to years.
SymptomsFirm lumps under the skin near lymph nodes (jaw, shoulder, flank, udder area). Internal form: chronic weight loss, poor condition, respiratory issues. Some goats are carriers with no visible abscesses.
TestBlood test (SHI or ELISA) detects antibodies. Culture of abscess material confirms the organism. Blood tests can have false positives and false negatives.
Cost$3 to $8 per animal (blood test). Culture: $15 to $30.
FrequencyTest annually. Test all new animals. Retest any animal with suspicious lumps.

Managing a CL-positive goat: If an abscess develops, isolate the goat immediately. The abscess can be lanced and flushed by a vet in an isolated area, with all contaminated material collected and burned or disposed of in sealed bags. The bacteria in CL pus is a zoonotic risk โ€” wear gloves and practice strict hygiene. Many breeders cull CL-positive animals to protect the rest of the herd.

Johne's Disease (Paratuberculosis)

Johne's (pronounced "YO-knees") is caused by Mycobacterium avium subspecies paratuberculosis (MAP). It causes chronic inflammation of the intestines, leading to progressive weight loss and eventually death. There is no cure.

AspectDetails
TransmissionFecal-oral route, primarily. Kids are most susceptible. Infected adults shed the bacteria in feces for months to years before showing symptoms. Also transmitted through infected milk and in utero.
SymptomsChronic wasting, weight loss despite good appetite, rough coat, decreased production. Diarrhea is less common in goats than in cattle with Johne's. Symptoms typically appear at 2 to 5 years of age.
TestBlood test (ELISA) for antibodies, or fecal culture/PCR for the organism. Blood tests have lower sensitivity in early infection. Fecal PCR is more sensitive but more expensive.
CostBlood ELISA: $5 to $10. Fecal PCR: $20 to $40.
ChallengeLong incubation period (1 to 3+ years). Goats can test negative for years while infected and shedding. This makes Johne's the hardest of the three to eradicate from a herd.

Other Tests to Consider

Q-Fever (Coxiella burnetii)

A bacterial infection that can cause late-term abortion in goats and is zoonotic โ€” it can infect humans, especially during kidding when the organism is shed in birth fluids. Consider testing if you have unexplained late-term abortions or if people on your farm are immunocompromised.

Brucellosis

Federally regulated disease. Most US herds are brucellosis-free, but testing may be required for interstate movement or sale at certain markets. Your state veterinarian can advise on requirements.

Pregnancy testing (BioPRYN)

While not a disease test, BioPRYN is a blood test that detects pregnancy-associated glycoproteins. Blood drawn at 30+ days post-breeding confirms pregnancy with high accuracy. Useful for pen-breeding situations where you are not sure which does settled.

When and How to Test

Annual herd testing

Testing new arrivals

Where to send samples: WADDL (Washington Animal Disease Diagnostic Lab) and TVMDL (Texas A&M Veterinary Medical Diagnostic Lab) are two of the most commonly used labs for goat disease panels. Many state veterinary diagnostic labs also offer these tests. Your vet can advise on the best lab for your area and often handles submission for you.

Keep test status where buyers can see it

Herd Manager stores each goat's CAE/CL/Johne's results and dates and flags retests, so your herd's health resume is always current.

Track testing free โ†’

Building a Clean Herd

The goal of disease testing is not just knowing your herd's status โ€” it is building and maintaining a disease-free herd. This requires a systematic approach:

CAE prevention program

  1. Test all animals annually
  2. Remove kids from positive dams immediately at birth (before nursing)
  3. Feed heat-treated colostrum (135 degrees F for 1 hour) and pasteurized milk
  4. Separate positive and negative animals โ€” do not share milking equipment, water buckets, or needles
  5. Use separate needles for each animal during vaccinations and blood draws
  6. Over time, cull positive animals as their productive life ends and retain only negative offspring

CL prevention

  1. Never buy an animal with visible lumps without having them cultured first
  2. Isolate any goat that develops a lump immediately
  3. If an abscess ruptures, clean and disinfect the area thoroughly. Contaminated soil can remain infectious for years.
  4. A CL vaccine exists (Colorado Serum Company) but is controversial โ€” it can cause injection site reactions and interferes with blood testing. Discuss with your vet.

General biosecurity

What to do if you get a positive result: Do not panic. A single positive test needs confirmation โ€” request a retest. If confirmed positive, work with your vet to develop a management plan. Depending on the disease, your herd size, and your goals, options range from culling the individual animal to implementing a test-and-separate program. The worst thing you can do is ignore a positive result โ€” it does not go away on its own, and it will spread.

Marketing a Tested Herd

Annual testing with documented negative results is one of the strongest marketing tools you have. When selling goats:

Frequently Asked Questions

What diseases should I test my goats for?

The big three are CAE, CL, and Johne's, all chronic and often symptomless for years. Depending on your situation you may also test for Q-fever, brucellosis (sometimes required for interstate movement), and use BioPRYN blood testing to confirm pregnancy.

How often should I test my goat herd for disease?

Test your entire herd once a year, ideally in late fall or winter, and test every new animal before introduction. Ask herd-visit pricing from your vet to lower per-animal cost, and in many states owners may draw blood themselves for approved labs.

How is CAE, CL, and Johne's testing done?

Mostly by a blood test (ELISA) that detects antibodies, sent to a lab like WADDL or TVMDL; CL abscesses can also be cultured and Johne's checked by fecal PCR. Costs run roughly $3 to $10 per animal for the blood panels.

What should I do if a goat tests positive?

Don't panic โ€” confirm with a retest first. If confirmed, work with your vet on a plan, which may range from culling the animal to a test-and-separate program. Ignoring a positive is the worst option, since these diseases spread and don't resolve on their own.

Why does disease testing matter when buying or selling goats?

Untested purchases are the most common way CAE, CL, and Johne's enter a clean herd, so buyers increasingly expect documented negative results. Annual testing with shared results is one of the strongest marketing tools a seller has.

Every goat's test status at a glance

Herd Manager stores disease-test results and dates on each goat's profile, shows your whole herd's status at a glance, flags when annual retests are due, and lets you share documentation with buyers.

Try Herd Manager Free →
Get it on Google Play
In Safari, tap the Share button (the square with an arrow), then choose Add to Home Screen. Herd Manager opens like an app โ€” no App Store needed.